Presented by Julie Jay, PhD, International Product Manager, Companion Diagnostics, Ventana Medical Systems, Inc., Tucson, AZ

This webinar will present an overview of the evolution of predictive diagnostics from the perspective of the regulatory terminology, the technology platforms and the utilization of biomarkers to aid in patient treatment decisions. Predictive diagnostics include companion diagnostics that select patients eligible for treatment as well as complementary diagnostics which provide information about how well a patient may respond to the therapy. Predictive diagnostics have utilized IHC, ISH as well as PCR, and NGS predictive diagnostics assays are currently under development. Due to the fact that protein and gene targets inform drug development to enable clinical success, predictive diagnostics will play an increasing role in personalized patient care.

Presented by Lisbeth A. O’Malley, BA, Employee Development Specialist, Beaumont, Troy, MI

In this webinar we will explore the toxic behaviors we find in the workplace. We will not only identify the disruptor, but those around them that also add to the situation. We will discuss the impact on the individuals, the team and the organization, and learn of some techniques to minimize this. We will close with strategies to alleviate the symptoms of being a “Toxic Handler”.

Presented by Pamela C. Gibson, MD, Division Chief of Anatomic Pathology, Associate Professor of Pathology,Renal Pathologist, Surgical Pathologist and Cytopathologist, University of Vermont Medical Center, Burlington, VT

Kidney biopsies can provide a wealth of information related to the diagnosis of kidney disease and the prognosis for the patient’s kidney function. Kidney biopsies however are not needed in all forms of kidney disease and are not without morbidity to the patient. This seminar will review the basic approach to the work up of kidney disease from the clinical perspective and introduce the audience to the reasons why a biopsy might be performed using real patient cases. The cases will help emphasize the role of special stains and immunofluorescence in the assessment of the kidney biopsy and will also address the importance of electron microscopy in the comprehensive diagnosis of kidney diseases.

Presented by Jennifer Freeland, BS, HTL (ASCP), Research & Development Manager, Thermo Fisher Scientific, Kalamazoo, MI

Tissue fixation is one of the very first chapters in all the histology text books for a very good reason: it is critical to specimen quality. With the emergence of clinically relevant biomarkers, there is the renewed focus on standardization of fixation and other pre-analytical variables: fixation has again become a central topic. This webinar will explore fixation in a historical sense, explore fixative types and chemistries, and compare results of poorly fixed tissues with well-fixed tissues. We will also consider the impact of fixation and other affiliated pre-analytical variables on modern biomarkers of clinical interest.

Presented by a member of Roche Diagnostics Medical and Scientific Affairs, Roche Diagnostics Corporation, Indianapolis, IN

The presentation provides an overview of: the relevance of PD-L1 as a cancer biomarker,the difference between the FDA classification of Complementary vs Companion Diagnostics, Targeted Therapy vs. Immunotherapy, Current FDA approved PD-L1 IHC assays and indications for use & scoring, Current FDA approved anti-PD1/anti-PD-L1 immunotherapies, Immunotherapy Clinical trial data

Presented by Douglas Yamanishi, PhD, Senior Marketing Manager, Advanced Staining, Sakura Finetek USA, Inc., Advanced Staining, Torrance, CA

This webinar will present an overview for utilizing whole blood as a “liquid biopsy”. Liquid biopsies may provide a means of monitoring the status of a cellular or tissue-based event (e.g. cancer or pregnancy) using a minimally invasive needle stick for specimen acquisition. The feasibility of using different cell enrichment (positive and negative) and cell identification (advanced staining) technologies will be presented.

Presented by Melinda M. Chow, MS, HT(ASCP)CM, Mohs Histotech, Memorial Sloan Kettering Cancer Center, Basking Ridge, NJ

Frozen sectioning is a quick procedure generally performed in a Mohs histopathology laboratory for a quick diagnosis while patients are waiting for the results. I will talk about the uses of frozen sections, different methods of freezing specimens, the art of cryosectioning and rapid hematoxylin and eosin staining of the frozen sections. I will also discuss the causes of the problems encountered and how to troubleshoot them each step of the way.

Presented by Elizabeth A. Chlipala, BS, HTL(ASCP)QIHC, Laboratory Manager, Partner, Premier Laboratory, LLC, Longmont, CO

This webinar will cover how standardization and overall quality of histology preparations are important to the successfulness in implementation of a digital pathology solution. There will be discussion on how to set up workflow, standard operating procedures, internal training and competency, and verification/validation of the scanning process. In addition the last portion of the webinar will discuss histology use cases.

Presented by Jacqueline Brooks, MB, SCT, HTL (ASCP), Laboratory Manager, Cunningham Pathology, Birmingham, AL

To fully understand how to prepare for a CAP inspection or any of the other Laboratory Regulatory inspections you must understand how the system works. This webinar will discuss the roles of CLIA, CAP, TJC and CMS. We will discuss the CAP application process for inspection and its timelines. We will spend considerable time on the CAP Checklists. We will review the changes made in 2016 and the presenter will share her experiences meeting the standards with emphasis on AP.

Presented by Debra Wood, M.S.Ed., HT(ASCP), Director-Histotechnology, Indiana University School of Medicine, Indianapolis, IN

This presentation will provide the basics of connective tissue stains as well as some not so common uses. We will look at images scanned on the Aperio and provided information on tools that can be used that are free or less expensive.

Presented by Angela McNabola, MS ,HT(ASCP)SLS ,QIHC, Manager , Pathology, Cytology, Histology, Bridgeport Hospital, Bridgeport, Connecticut

There are many things to consider when preparing your organization for an emergency event, whether it is chemical spill, a man made event or natural disaster. The goal is to have a well rehearsed action plan before it happens. This webinar will discuss what CBRNE events are, how to perform a hazard risk assessment and discuss what resources and procedures are needed to be prepared.

Presented by Richard Cartun, MS, PhD, Hartford Hospital, Hartford, CT
This webinar will open with a quick overview of the immunohistochemistry process, but will primarily discuss basic troubleshooting in the clinical IHC laboratory. The troubleshooting of manual protocols will be reviewed, as well as troubleshooting automation across multiple platforms.